منابع مشابه
C Cognition and behaviour in mot or neurone disease
Current Opinion in Neurology 2010, 23:638–642 Purpose of review Motor neurone disease has traditionally been considered a pure motor syndrome which spares aspects of cognition and behaviour, although in recent years it has been suggested that up to 50% of patients with motor neurone disease may develop frontal dysfunction which, in some cases, is severe enough to reach criteria for frontotempor...
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Neurological involvement associated with inflammatory bowel disease is well established though rarely reported in the literature. The coexistence of motor neurone disease with ulcerative colitis has never been previously documented. The case of a 53-year-old Indian male with distal ulcerative colitis who, two and a half years later, developed dysarthria, dysphagia, a wasted fasciculating tongue...
متن کاملAmyotrophic Lateral Sclerosis ( ALS ) or Motor Neurone Disease
In this paper, I attempt to combine previous research data in order to design a new mechanism by which neurotrophic factors may be delivered to their target sites. Although this idea is only theoretical, is provides a novel mechanism for future drug designs involving neurotrophic factors. In this paper, I use motorneurone disease as an example, and present a theoretical drug design for this dis...
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Alzheimer's disease (AD) is a degenerative disorder where the distribution of pathology throughout the brain is not random but follows a predictive pattern used for pathological staging. While the involvement of defined functional systems is fairly well established for more advanced stages, the initial sites of degeneration are still ill defined. The prevailing concept suggests an origin within...
متن کاملFamilial Motor Neurone Disease.
Motor neurone disease is a relatively common condition with a gross prevalence rate of about 4 per 100,000 (Kurland, 1957). It is fairly uniformly distributed throughout the world, with the exception of the Chamorro population of Guam and Rota in the Mariana Islands and Chamorro emigrants in California. In this ethnic group the prevalence is about 420 per 100,000 (Kurland, 1957) and familial ex...
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ژورنال
عنوان ژورنال: BMJ
سال: 1916
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.2895.888